In vitro evaluation shows lycorine's antispasmodic effects in rabbit intestine, suggesting potential therapeutic uses.
Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant family. It has been reported to exhibit a wide range of physiological effects, including the potential effect against cancer. The antispasmodic activity was investigated in vitro using rabbit intestine, and the antioxidant activity was evaluated by DPPH assay. The results indicated that lycorine has an irreversible relaxant property on the isolated rabbit jejunum. Whereas, it did not show a significant antioxidant activity toward the DPPH free radical in comparison with ascorbic acid.
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Bendaif et al. (2025) studied this question.
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