What question did this study set out to answer?

This review aims to explore how surgery is integrated into the multidisciplinary treatment of colorectal liver metastases.

February 5, 2026CancersOpen Access

How to Integrate Surgery into the Multidisciplinary Treatment of Liver-Only Metastatic Colorectal Cancer

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Narrative review demonstrates enhanced outcomes in liver metastatic colorectal cancer through multidisciplinary management and surgical integration.

This review aims to explore how surgery is integrated into the multidisciplinary treatment of colorectal liver metastases.
Narrative review of contemporary practices in CRLM management.
Analysis of surgical techniques and their integration with oncology and radiology.
Discussion of criteria for surgery such as tumor burden and molecular profile.
Highlights the importance of multidisciplinary team meetings for treatment decision-making.
Reviews criteria for determining resectability and planning surgical approaches.
Summarizes the role of parenchyma-sparing techniques and local therapies in treatment algorithms.

Lundgren et al. (2026) studied this question.

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Narrative review demonstrates enhanced outcomes in liver metastatic colorectal cancer through multidisciplinary management and surgical integration.