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January 1, 2026RSC AdvancesOpen Access

A Ru( ii )-arene complex with promising anti-Aβ activity

Ryan M. Hacker J. Smith David C. Platt Maria Loughlin Emma N. Grabowski William W. Brennessel Mike Jones Michael I. Webb

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Key Points

To investigate the anti-Aβ activity of a novel ruthenium(II)-arene complex.
Synthesis of ruthenium(II)-arene complex
In vitro assays to study amyloid-beta peptide aggregation
The complex significantly modulates amyloid-beta aggregation
Demonstrated potential as an anti-Aβ therapeutic agent

Implication

Novel ruthenium(II)-arene complex shows anti-Aβ activity, suggesting its potential in related therapies.

Abstract

A novel ruthenium( ii )-arene complex was shown to significantly modulate the aggregation of the amyloid-beta peptide.

Discussion

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Cite This Study

Hacker et al. (2026) studied this question.

synapsesocial.com/papers/6984359ef1d9ada3c1fb4a68 https://doi.org/10.1039/d5ra08313c

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