This randomized trial investigates the influence of coordination lability and aromaticity on amyloid-β targeting by transition-metal complexes, suggesting new therapeutic strategies.
The interaction of transition-metal complexes with amyloidogenic peptides represents a promising strategy for controlling pathological protein aggregation through coordination chemistry and supramolecular effects. Herein, we investigate a series of η⁶-arene...
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Florio et al. (2026) studied this question.
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