Case report reveals cutaneous reactions following zoledronic acid in a cancer patient, suggesting rare side effects.
Zoledronic acid is an amino-bisphosphonate, commonly used for the treatment of osteoporosis, management of bone metastasis, multiple myeloma, and Paget’s disease. Although it is associated with some common side effects like weakness and musculoskeletal pain, cutaneous reactions/side effects are extremely rare. In this case report, we have discussed a 72-year-old patient with metastatic breast carcinoma who experienced cutaneous reactions after zoledronic acid injection. The patient was treated with topical steroids, and the reactions did not recur after stopping the zoledronic injection.
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Biswas et al. (2025) studied this question.
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