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Experimental study shows oleacein reduces inflammation in human synovial cells, suggesting dietary strategies for arthritis management.
OLA protects SW982 cells from IL-1β/LPS + ATP-induced inflammation and oxidative stress via MAPK, inflammasome, NF-κB, Keap1/Nrf2/HO-1 and epigenetic modulation, reducing cytokines, MMPs and COX-2/PGE 2 , suggesting a dietary strategy for arthritis.
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Muñoz-García et al. (2026) studied this question.
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