Key result
Incident AF linked to a ~2.7 decline in word fluency in patients with subclinical cerebral infarcts.
Why the study?
Does incident atrial fibrillation increase cognitive decline in stroke-free individuals?
Does incident atrial fibrillation increase cognitive decline in stroke-free individuals?
Incident atrial fibrillation is associated with cognitive decline in stroke-free individuals, a relationship that appears to be mediated by the presence or development of subclinical cerebral infarcts.
No takes yet. Share an insight, caveat, or question.
Supports AF-cognitive decline link via subclinical infarcts in stroke-free adults; leaves open whether screening or intervention modifies risk.
Chen et al. (2014) studied this question. Incident atrial fibrillation was associated with a decline in word fluency by −2.65 in participants with subclinical cerebral infarcts (P = 0.002).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: