Key result
Recent research shifts clinical understanding and treatment decisions for four types of intracardiac thrombus.
Why the study?
Intracardiac thrombi are frequently encountered in clinical practice, yet evidence-based guidance for clinicians managing these patients is often limited.
This review summarizes current knowledge on the diagnosis and management of four key types of intracardiac thrombi, highlighting the need for more robust prospective trials.
Shifting intracardiac thrombus practices warrant caution without stronger data; leaves open the need for prospective trials.
Intracardiac thrombi can occur in a variety of locations and are frequently encountered in clinical practice. Yet evidence-based guidance for clinicians managing patients with intracardiac thrombi is often limited. This review summarizes what is known regarding the prevalence of intracardiac thrombus, diagnostic strategies, clinical relevance, and treatment options, focusing on four specific types of thrombus for which recent research has shifted clinical understanding and treatment decisions: (1) left atrial appendage thrombus, (2) cardiac implantable electronic device lead thrombus, (3) bioprosthetic aortic valve thrombus, and (4) left ventricular thrombus. Additional studies, ideally prospective, randomized, and head-to-head in design, are needed to better inform best practices in patients with intracardiac thrombi.
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Patel et al. (2021) studied this question. Recent research has shifted clinical understanding and treatment decisions for four specific types of intracardiac thrombus, highlighting the need for better evidence-based practices.
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