Exploratory evaluation of early 68Ga-FAPI-46 PET/CT volume-based parameters in systemic sclerosis-associated interstitial lung disease

Key Points

• The research aims to evaluate early volume-based parameters of 68Ga-FAPI-46 PET/CT in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD).
• Conducted exploratory study using PET/CT imaging with 68Ga-FAPI-46
• Focused on volume-based parameters in patients
• Analyzed association with disease progression
• Identified early PET parameters associated with recent disease progression
• Highlighted preliminary thresholds that may indicate significance
• Suggests potential for clinical utility in treatment-response studies