Key result
Lumbar puncture with acetazolamide resolves IIH-induced hemiparesis within 1 week in a case report.
Case Report (n=1)
No
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Case report reveals improved outcomes in a woman with hemiparesis due to idiopathic intracranial hypertension, suggesting quick diagnosis is vital.
Idiopathic intracranial hypertension (IIH) presenting with focal neurological deficits is rare and may mimic acute stroke, complicating timely diagnosis. We report the case of a 43-year-old Malay woman with progressive headache, intermittent visual symptoms, and acute-onset, progressive right-sided weakness over two days. Dilated fundus examination revealed bilateral grade 2 papilledema, and neurological examination showed mild hemiparesis. Non-contrast CT and CT angiography of the brain were normal. Lumbar puncture (LP) demonstrated elevated opening pressure with normal CSF findings. She improved significantly following LP and acetazolamide, with complete resolution of hemiparesis within one week. This uncommon presentation highlights the importance of prompt neuroimaging, early ophthalmological assessment, and LP. IIH should be considered in patients with persistent headache and acute hemiparesis once structural and vascular causes have been excluded.
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Azhari et al. (2026) conducted a case report in Idiopathic intracranial hypertension presenting with reversible hemiparesis (n=1). Therapeutic lumbar puncture and acetazolamide was evaluated on Resolution of right-sided hemiparesis and visual symptoms. Lumbar puncture drainage of 18 mL CSF and acetazolamide 500 mg twice daily resulted in complete resolution of right-sided hemiparesis within 1 week in a patient with IIH.
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