Why the study?
To investigate whether cardiometabolic index, visceral adiposity index, dysfunctional adiposity index, and body adiposity index compared with waist circumference and body mass index could predict future hypertension.
Do novel anthropometric indices (cardiometabolic index, visceral adiposity index, dysfunctional adiposity index, body adiposity index) predict incident hypertension better than traditional measures (waist circumference, body mass index)?
Cohort (n=597)
Do novel anthropometric indices (cardiometabolic index, visceral adiposity index, dysfunctional adiposity index, body adiposity index) predict incident hypertension better than traditional measures (waist circumference, body mass index)?
Hazard Ratio: 1.944 (95% CI 1.381–2.738)
p-value: p=< 0.001
Traditional anthropometric measures like waist circumference and BMI remain superior to novel adiposity indices for predicting incident hypertension over a 15-year period.
Traditional measures should remain primary for hypertension risk assessment; supports consensus while leaving open incremental value of novel indices.
Aim To investigate whether cardiometabolic index,visceral adiposity index, dysfunctional adiposity index and body adiposity index compared with waist circumference and body mass index could predict future hypertension in a 15-year prospective study. Methods The data were collected in 1992 and recollected in 2007 from the same group of 597 individuals. Anthropometric indices and biochemical data were obtained. Cox’s proportional hazards regression models were used to estimate the hazard ratios of anthropometric measures. The discriminatory power of anthropometric measures for incident hypertension were assessed by Receiver Operating characteristic Curve. Results During follow-up, 265 participants were newly diagnosed with hypertension. In multivariable Cox regression analysis after adjusting potential for confounders, cardiometabolic index [HR: 1.944 (95% CI: 1.381–2.738) per SD; P < 0.001], visceral adiposity index [HR: 1.499 (95% CI: 1.068–2.104) per SD; P =0.019], dysfunctional adiposity index [HR: 1.422 (95% CI: 1.017–1.990) per SD; P =0.040], body adiposity index [HR: 1.864 (95% CI: 1.297–2.678) per SD; P =0.001], waist circumference [HR: 2.432 (95% CI: 1.670–3.543) per SD; P < 0.001], waist-to-height ratio [HR: 2.515 (95% CI: 1.746–3.622) per SD; P < 0.001] and body mass index [HR: 2.523 (95% CI: 1.773–3.592) per SD; P < 0.001] were significantly associated with incident hypertension. Additionally, waist circumference product had the highest AUC at 0.649 (95% CI: 0.605–0.693), followed by body mass index at 0.648 (95% CI: 0.603–0.692) and waist-to-height ratio at 0.646 (95% CI: 0.601–0.690) then by cardiometabolic index at 0.603 (95% CI: 0.557–0.649). Conclusions Cardiometabolic index,visceral adiposity index, dysfunctional adiposity index and body adiposity index were independent predictors of future hypertension. The discriminatory power of these indexes product for hypertension prediction were lower than that of waist circumference and body mass index.
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Pan et al. (2025) conducted a cohort in hypertension (n=597). Anthropometric measures (cardiometabolic index, visceral adiposity index, dysfunctional adiposity index, body adiposity index) vs. waist circumference and body mass index was evaluated on incident hypertension (HR 1.944, 95% CI 1.381-2.738, p=< 0.001).
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