Acid-responsive metal organic frameworks with photothermal effects for osteoarthritis multiple therapy

January 1, 2026RSC AdvancesOpen Access

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Key Points

The aim is to explore the effects of acid-responsive metal organic frameworks in treating osteoarthritis, focusing on their photothermal abilities.
Developed metal organic frameworks responsive to acidic environments.
Examined photothermal effects and their impact on inflammation.
Assessed therapeutic outcomes in osteoarthritis models.
Demonstrated significant reduction in inflammation associated with osteoarthritis.
Observed reversible effects indicating potential early intervention benefits.
Identified enhanced therapeutic response through multiple therapy mechanisms.

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Experimental investigation identifies photothermal effects targeting inflammation in osteoarthritis, suggesting a novel treatment approach.

Early osteoarthritis (OA) with reversible ability appears to lack features other than intense acute inflammation.

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Feng et al. (2026) studied this question.

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