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The study aims to explore clinical characteristics and reasons for misdiagnosis of arsenic-induced peripheral neuropathy.

February 8, 2026Frontiers in ToxicologyOpen Access

A case report of arsenic-induced peripheral neuropathy misdiagnosed as Guillain-Barré syndrome

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The study aims to explore clinical characteristics and reasons for misdiagnosis of arsenic-induced peripheral neuropathy.
Case report of a 58-year-old male with symptoms of peripheral neuropathy
Initial misdiagnosis as Guillain-Barré syndrome
Analysis of clinical features, diagnostic process, and treatment
Literature review to support findings
Patient exhibited progressive peripheral neuropathy and facial palsy
Initial treatment included standard immunotherapy with no improvement
Critical diagnostic clues included history of herbal medicine use and distinctive skin findings
Laboratory tests confirmed high arsenic levels in nail and hair samples

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A case report reveals arsenic-induced peripheral neuropathy mimicking Guillain-Barré syndrome, suggesting importance of proper diagnosis.

Fu et al. (2026) studied this question.

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A case report reveals arsenic-induced peripheral neuropathy mimicking Guillain-Barré syndrome, suggesting importance of proper diagnosis.