This systematic review examines aerobic exercise's effects on VEGF levels in adults, indicating no significant influence overall.
It appears that aerobic exercise does not have significant overall influence on circulating VEGF levels. However, VEGF reductions may subsequently occur after short-duration interventions. Further research is needed with larger high-quality RCTs to verify these associations and further explore the mechanisms.
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Zanganeh et al. (2026) studied this question.
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