Key result
Regular aerobic exercise improves FMD and reduces PWV in overweight and obese older adults.
Why the study?
The effects of aerobic exercise on vascular endothelial function in obese and overweight older adults remain controversial.
Does regular aerobic exercise improve vascular function in overweight or obese older adults?
Meta-Analysis
Does regular aerobic exercise improve vascular function in overweight or obese older adults?
Regular aerobic exercise, particularly when performed at least 3 times per week for over 24 weeks, improves vascular endothelial function and reduces arterial stiffness in overweight and obese older adults.
Answers are grounded in this paper and cite their sources.
Supports recommending sustained aerobic exercise for vascular health in overweight/obese older adults; reinforces intervention evidence in this population.
Background: Overweight and obese older adults have a high risk for developing cardiovascular disease. Aerobic exercise is a valuable strategy to improve vascular health, but the effects of aerobic exercise on vascular endothelial function in obese and overweight older adults remain controversial. The purpose of this meta-analysis was to investigate the effects of aerobic exercise on vascular function in obese and overweight older adults with or without comorbidity. Methods: A systematic literature search for related studies published in English was conducted between January 1989 and October 30, 2022, in the PubMed, Embase, and Cochrane Library databases. A random effects model was chosen for meta-analysis, which calculated the effect sizes of control and intervention groups after exercise intervention using standardized mean differences (SMDs) corrected for Hedges' g bias and 95% confidence intervals (95% CIs). Results: = 31.1%, P = 0.012] in obese and overweight older adults with or without CVD. Conclusion: In obese and overweight older adults with or without comorbidity, regular aerobic exercise for more than 24 weeks improved FMD by small effect sizes and exercise for more than three times per week improved FMD by moderate effect sizes and regular aerobic exercise reduced PWV by small effect sizes and had no influence on Aix. Taken together, it was recommended that obese and overweight older adults should adhere to regular aerobic exercise, training at least 3 times per week for better results.
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Li et al. (2023) conducted a meta-analysis in Overweight or obese older adults. Regular aerobic exercise vs. Control was evaluated on Vascular function (FMD, PWV, Aix) (p=0.012). Regular aerobic exercise for >24 weeks and ≥3 times per week improved flow-mediated dilation and reduced pulse wave velocity in overweight and obese older adults (P=0.012).
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