Effect of geriatric co-management on independence, quality of life, and severe toxicity in vulnerable older patients with cancer: Results of a randomized clinical trial

Gabriele Ihorst; Elisabeth Jentschke; Kathrin Tatschner; Carmen Roch; Birgitt van Oorschot; Peter Baier; Bernhard Geyer; Miriam Hüttmeyer; Christoph Hohlbein; Anna Heckers; Johanna Gerber; Barbara Deschler-Baier

doi:10.1016/j.jgo.2026.102896

February 4, 2026Journal of Geriatric OncologyOpen Access

Effect of geriatric co-management on independence, quality of life, and severe toxicity in vulnerable older patients with cancer: Results of a randomized clinical trial

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Key Points

The aim is to evaluate the impact of geriatric co-management on independence, quality of life, and severe toxicity in older cancer patients.
Randomized clinical trial design
Intervention focused on geriatric co-management
Population involves vulnerable older patients with cancer
Assessment of quality of life, independence, and toxicity
Analysis of hospitalizations due to interventions
No significant impact on quality of life or independence observed
Reduction in severe toxicity noted
Potential decrease in unplanned hospitalizations
Findings suggest benefits of integrating geriatric approaches in oncology care

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Implication

Randomized clinical trial reveals geriatric co-management may reduce severe toxicity in older cancer patients, highlighting the need for integration in oncology care.

Abstract

The interventions showed a consistent, yet statistically insignificant, impact on quality of life and independence. Importantly, it was associated with a reduction in severe toxicity and may have led to fewer unplanned hospitalizations. Findings support further integration of geriatric co-management into routine oncology care for older adults with cancer.

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Ihorst et al. (2026) studied this question.

synapsesocial.com/papers/698827570fc35cd7a8846013 https://doi.org/10.1016/j.jgo.2026.102896

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Effect of geriatric co-management on independence, quality of life, and severe toxicity in vulnerable older patients with cancer: Results of a randomized clinical trial

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Effect of geriatric co-management on independence, quality of life, and severe toxicity in vulnerable older patients with cancer: Results of a randomized clinical trial

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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