Laboratory synthesis reveals antibacterial properties of new compounds against Staphylococcus aureus and Escherichia coli, suggesting potential therapeutic use.
A series of new 5-aryl-4-acyl-3-hydroxy-1-(4-methoxyphenyl)-3-pyrrolin-2-ones was synthesized by the reacting of methyl esters of aroylpyruvic acids with a mixture of aromatic aldehyde and p-anisidine. Antibacterial activity of the obtained compounds was studied in vitro against Staphylococcus aureus and Escherichia coli strains.
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N. N. Kasimova (2025) studied this question.
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