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February 8, 2026

Design, Synthesis, and Application of a Novel Schiff Base-1,2,3-triazole Fluorescent Probe for Selective Detection of Aluminum Ions.

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Authors

CLChunyang LiuAnhui UniversityJCJun-Feng ChenHainan Normal UniversityLWLuyong WuHainan Normal University

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Implication

This research demonstrates a new fluorescent probe that detects aluminum ions in water, indicating potential environmental and biological applications.

Key Points

  • Evaluate the effectiveness of a new fluorescent probe for selectively detecting aluminum ions.
  • Designed and synthesized a fluorescent probe G3
  • Characterized using 1H NMR, 13C NMR, and MS
  • Conducted Job's plot analysis and NMR titrations to study binding
  • Utilized DFT and quantum chemical calculations for sensing mechanism
  • Demonstrated applicability in environmental samples and cellular imaging
  • G3 shows a selective fluorescence enhancement for Al3+
  • Achieves a detection limit of 1.162 nM
  • Confirms 1:1 binding stoichiometry with aluminum ions
  • Demonstrates low cytotoxicity and biocompatibility
  • Effective for detection in both water samples and cellular systems.

Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/698827b40fc35cd7a8846ac8https://doi.org/10.1002/bio.70433
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