What question did this study set out to answer?

To report a rare case of mullerianosis in the urinary bladder and emphasize the importance of accurate diagnosis.

February 8, 2026Open Access

Mullerianosis of the Urinary Bladder: A Rare Case Report

Key Points

To report a rare case of mullerianosis in the urinary bladder and emphasize the importance of accurate diagnosis.
Case report of a 40-year-old woman presenting with pelvic pain and dysuria.
Transurethral resection of a bladder mass was performed for histopathological examination.
Immunohistochemistry assessed ER/PR positivity in glandular epithelium and CD10 positivity in stroma.
The bladder mass measured 3.2×2.5 cm and revealed endocervical glands and endometrial stroma.
Diagnosis of mullerianosis was confirmed through immunohistochemistry.
The patient remained asymptomatic for 8 years with no recurrence after the diagnosis.

Abstract

Endocervicosis, endometriosis, and endosalpingosis are choristomas derived from Müllerian tissue, collectively termed Müllerianosis. We report a 40-year-old woman with pelvic pain and dysuria who presented with a 3.2×2.5 cm bladder mass four years post-hysterectomy. Transurethral resection revealed endocervical glands and endometrial stroma deep in the bladder wall. Immunohistochemistry confirmed ER/PR positivity in glandular epithelium and CD10 positivity in stroma, establishing the diagnosis of Müllerianosis. Outcome: The patient remained asymptomatic with no recurrence over 8 years of clinical and cystoscopic follow-up. Müllerianosis is a rare benign bladder lesion that can mimic malignancy. Accurate histopathological diagnosis with immunohistochemistry is essential to avoid unnecessary radical surgery and enable hormonal therapy when indicated.

Mark Helpful

Bookmark

Relay

View Full Paper