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February 8, 2026European Heart Journal0 citations

Cardiac Rehabilitation Improves Survival in Acute Coronary Syndrome Survivors

Participation in a comprehensive cardiac rehabilitation program improves mid- and long-term prognosis in survivors of acute coronary syndrome

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Why the study?

Does participation in a comprehensive cardiac rehabilitation program improve survival in early survivors of acute coronary syndrome?

Population

66,095 early survivors of acute coronary syndrome from the Hungarian National Myocardial Infarction Register.

Comparison

Comprehensive cardiac rehabilitation program… vs No participation in the comprehensive cardiac…

Design

Cohort

Follow-up

1 year to long-term

Key result

Participation in comprehensive cardiac rehabilitation reduced 1-year mortality by 42% in STEMI patients and improved long-term survival after acute coronary syndrome.

Authors

CSC S SariCHC M HeeschPAP Andreka

Discussion

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Member takes

Overview

Supports wider cardiac rehabilitation referral post-ACS; extends observational evidence but leaves causal benefit open.

Key Points

  • Evaluate the impact of comprehensive cardiac rehabilitation on survival in patients with acute coronary syndrome.
  • Retrospective analysis of data from the National Myocardial Infarction Register in Hungary.
  • Included 76,095 early survivors of acute coronary syndrome post-30 days.
  • Analyzed factors predicting survival including participation in cardiac rehabilitation and percutaneous coronary interventions.
  • Participation in cardiac rehabilitation reduced 1-year mortality by 42% for ST-elevation myocardial infarction (STEMI) patients.
  • Improved long-term survival rates across various patient subgroups.
  • Only 21% of eligible patients participated in cardiac rehabilitation programs.

Structured PICO

Does participation in a comprehensive cardiac rehabilitation program improve survival in early survivors of acute coronary syndrome?

P
Population
66,095 early survivors of acute coronary syndrome (alive after 30 days of the index event) from the Hungarian National Myocardial Infarction Register (2014-2019).
I
Intervention
Comprehensive cardiac rehabilitation program (CCR) including supervised physical exercise and patient education on smoking cessation, dietary changes, and medication compliance.
C
Comparator
No participation in the comprehensive cardiac rehabilitation program.
O
Outcome
1-year mortality and long-term survival.hard clinical

Participation in a comprehensive cardiac rehabilitation program significantly reduces 1-year mortality in early survivors of ACS, though it remains severely underutilized with only a 21% participation rate.

Cite This Study

Sari et al. (2025) studied this question. Participation in comprehensive cardiac rehabilitation reduced 1-year mortality by 42% in STEMI patients and improved long-term survival after acute coronary syndrome.

synapsesocial.com/papers/698828410fc35cd7a8847a66https://doi.org/10.1093/eurheartj/ehaf784.3642
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