Volume compensation mechanisms occur after VATS segmentectomy, with more pronounced volume reduction following upper-lobe resections compared to lower-lobe resections. The absence of contralateral volumetric compensation may allow subsequent compensatory responses to occur and potentially contribute to a better preservation of lung function in patients undergoing additional pulmonary resections. Characterizing these patterns is important for surgical planning and optimizing postoperative management in patients undergoing segmentectomy for early-stage NSCLC.
Dewarrat et al. (2026) studied this question.