The study aims to investigate the effects of Panax notoginseng flower extract on depression-like behaviors in mice induced by chronic unpredictable mild stress.
Utilized a mouse model subjected to chronic unpredictable mild stress.
Administered Panax notoginseng flower extract to assess its impact on behavior.
Evaluated behavioral changes and neuroinflammation levels in the brain.
Panax notoginseng extract significantly reduced depression-like behaviors in mice.
The treatment led to a decrease in markers of neuroinflammation in the brain.
Abstract
PNF ameliorates CUMS-induced depression-like behaviors in mice, which may be mainly related to reducing neuroinflammation in the brain.