Key result
Illicit drug use in ACS is linked to an ~84% increase in in-hospital mortality or cardiac arrest.
Why the study?
Does illicit drug use worsen in-hospital outcomes in patients admitted for acute coronary syndrome?
Cohort (n=16,132)
Yes
Does illicit drug use worsen in-hospital outcomes in patients admitted for acute coronary syndrome?
Odds Ratio: 1.84 (95% CI 1.14–2.98)
Absolute Event Rate: 4.2% vs 3.9%
p-value: p=0.001
No takes yet. Share an insight, caveat, or question.
Illicit drug use is an independent predictor of in-hospital death or cardiac arrest in patients admitted for acute coronary syndrome, despite these patients being younger and having fewer traditional comorbidities.
Bouleti et al. (2025) conducted a cohort in Acute coronary syndrome (n=16,132). Illicit drug use vs. No illicit drug use was evaluated on Composite of all-cause death and cardiac arrest (adjusted OR 1.84, 95% CI 1.14-2.98, p=0.001). Illicit drug use was independently associated with an increased risk of in-hospital death or cardiac arrest in patients with acute coronary syndrome (adjusted OR 1.84; 95% CI 1.14-2.98; P=0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: