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February 8, 2026Open Access

Precision Neuromodulation Treatment Reverses Motor and Cognitive Slowing After Stroke: Clinical and Neurophysiological Evidence.

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Authors

GRGianna Carla RiccitelliLaboratory for Biomedical NeurosciencesRGRiccardo GironiLaboratory for Biomedical NeurosciencesEREdoardo RicciLaboratory for Biomedical Neurosciences

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Implication

Clinical evidence shows precision neuromodulation improves motor and cognitive functions in a stroke patient, implying new rehabilitation strategies.

Key Points

  • This research aims to explore the effectiveness of precision neuromodulation in reversing motor and cognitive slowing after a stroke.
  • Conducted 20 sessions of high-frequency repetitive transcranial magnetic stimulation and cognitive training over 4 weeks.
  • Targeted interventions included stimulation of the supplementary motor area and bilateral temporo-parietal junctions.
  • Performed motor and cognitive assessments along with quantitative EEG evaluations before and after treatment.
  • Upper extremity speed and coordination improved significantly by 66% (dominant hand) and 74% (non-dominant hand) on the Finger Tapping Test.
  • Finger dexterity increased by 25% (dominant hand) and 19% (non-dominant hand) on the Nine-Hole Peg Test.
  • Cognitive scores revealed improvements in alertness (58%), visual exploration (25%), and flexibility (24%).
  • qEEG showed increases in alpha (79%), gamma (33%), and beta (10%) power, indicating enhanced cortical rhythms.

Cite This Study

Riccitelli et al. (2026) studied this question.

synapsesocial.com/papers/698828fd0fc35cd7a8848f00https://doi.org/10.48620/94279
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Precision Neuromodulation Treatment Reverses Motor and Cognitive Slowing After Stroke: Clinical and Neurophysiological Evidence2026
  2. 2Neuromodulation and rehabilitation of post-stroke cognitive impairment: challenges and prospects2026 · 2 citations
  3. 3Combined Effect of Repetitive Transcableranial Magnetic Stimulation and Cognitive Rehabilitation on Working Memory of Patients with Chronic Stroke2022
  4. 4Optimization of Stroke Rehabilitation with a Combination of Repetitive Transcranial Magnetic Stimulation, Brainwave Entrainment, and Dry Needling: A Case Report2025
  5. 5Case Report: 40Hz multi-target transcranial alternating current stimulation combined with rehabilitation for post-stroke cognitive impairment2025 · 2 citations