Key result
The 9-point HOME score, integrating four echocardiographic parameters, demonstrated excellent discrimination for successful bicuspid aortic valve repair (AUC 0.89; 95% CI 0.79-0.94).
Why the study?
A standardized and reliable echocardiographic scoring system for predicting bicuspid aortic valve reparability was lacking.
Does the HOME score predict successful bicuspid aortic valve repair in patients undergoing surgery for aortic regurgitation?
Observational (n=203)
Does the HOME score predict successful bicuspid aortic valve repair in patients undergoing surgery for aortic regurgitation?
Answers are grounded in this paper and cite their sources.
The novel 9-point HOME score, based on four routine TEE parameters, provides excellent discrimination for predicting successful bicuspid aortic valve repair.
OBJECTIVES: To develop and internally validate a novel scoring system for bicuspid aortic valve (BAV) reparability based on routinely collected transoesophageal echocardiography (TEE) parameters. METHODS: We conducted a retrospective analysis of 203 consecutive BAV patients who underwent surgery for aortic regurgitation between 2018 and 2024. Ten preoperative TEE parameters associated with valve repair were systematically analysed; significant variables were included in a multivariate analysis and then integrated into a scoring system. RESULTS: Four baseline TEE measurements emerged as independent parameters associated with BAV repair: geometric height ≥ 18 mm (odds ratio [OR]: 8.05; 95% confidence interval (CI): 3.15 to 22.94; P ≤ .001), commissural orientation ≥ 140° (OR: 8.29; 95% CI: 2.67-25.67; P ≤ .001), good cusp quality (OR: 20.4; 95% CI: 6.59-63.53; P ≤ .001), and preserved cusp mobility (OR: 11.1; 95% CI: 3.98-31.45; P ≤ .001). We integrated these findings into the simple, 9-point HOME score. The score demonstrated excellent discrimination for successful repair (area under the curve = 0.89, 95% CI: 0.79-0.94), effectively stratifying patients into groups with low (score 0-4), intermediate (5-6), and high (7-9) likelihoods of a valve-preserving surgery. CONCLUSIONS: The HOME score may help identify BAV patients with a high probability of preserving surgery in a more standardized and reliable way.
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Italiano et al. (2026) conducted an observational in Bicuspid aortic valve (BAV) requiring surgery for aortic regurgitation (n=203). HOME score was evaluated on Successful bicuspid aortic valve repair (AUC 0.89, 95% CI 0.79-0.94). The 9-point HOME score, integrating four echocardiographic parameters, demonstrated excellent discrimination for successful bicuspid aortic valve repair (AUC 0.89; 95% CI 0.79-0.94).
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