Key result
German Aortic Valve Score outperforms EuroSCORE II in predicting operative mortality for isolated AVR.
Why the study?
Does the German Aortic Valve Score improve operative mortality risk prediction compared to EuroSCORE II in patients undergoing isolated aortic valve replacement?
Observational (n=35)
No
Does the German Aortic Valve Score improve operative mortality risk prediction compared to EuroSCORE II in patients undergoing isolated aortic valve replacement?
The German Aortic Valve Score demonstrated better discriminative capacity than EuroSCORE II for predicting operative mortality in patients undergoing isolated aortic valve replacement.
Answers are grounded in this paper and cite their sources.
May improve risk prediction in isolated AVR; leaves open validation in larger prospective cohorts before practice change.
OBJECTIVE:: Risk assessment for operative mortality is mandatory for all cardiac operations. For some operation types such as aortic valve repair, EuroSCORE II overestimates the mortality rate and a new scoring system (German AV score) has been developed for a more accurate assessment of operative risk. In this study, we aimed to validate German Aortic Valve Score in our clinic in patients undergoing isolated aortic valve replacement. METHODS:: A total of 35 patients who underwent isolated open aortic valve replacement between 2010 and 2013 were included. Patients with concomitant procedures and transcatheter aortic valve implantation were excluded. Patients' data were collected and analyzed retrospectively. Patients' risk scores EuroSCORE II were calculated online according to criteria described by EuroSCORE taskforce, Aortic Valve Scores were also calculated. RESULTS:: The mean age of patients was 61.14±13.25 years (range 29-80 years). The number of female patients was 14 (40%) and body mass index of 25 (71.43%) patients was in range of 22-35. Mean German Aortic Valve Score was 1.05±0.96 (min: 0 max: 4.98) and mean EuroSCORE was 2.30±2.60 (min: 0.62, max: 2.30). The Aortic Valve Score scale showed better discriminative capacity (AUC 0.647, 95% CI 0.439-0.854). The goodness of fit was x2HL=16.63; P=0.436). EuroSCORE II scale had shown less discriminative capacity (AUC 0.397, 95% CI 0.200-0.597). The goodness of fit was good for both scales. The goodness of fit was x2HL=30.10; P=0.610. CONCLUSION:: In conclusion, German AV score applies to our population with high predictive accuracy and goodness of fit.
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Kalender et al. (2017) conducted an observational in Isolated aortic valve replacement (n=35). German Aortic Valve Score vs. EuroSCORE II was evaluated on Discriminative capacity for operative mortality (AUC, 95% CI 0.439-0.854). The German Aortic Valve Score demonstrated better discriminative capacity for operative mortality compared to EuroSCORE II (AUC 0.647 vs 0.397) in patients undergoing isolated aortic valve replacement.
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