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May 31, 2017Science Translational MedicineOpen Access

Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice

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Abstract

C3 deficiency protects against hippocampal neurodegeneration and cognitive decline in aged APP/PS1 mice despite abundant Aβ plaques.

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Cite This Study

Shi et al. (2017) studied this question.

synapsesocial.com/papers/69889691e31b71e658b2dfd4 https://doi.org/10.1126/scitranslmed.aaf6295

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