What question did this study set out to answer?

The aim is to evaluate the effectiveness of methylene blue-enhanced therapies against Staphylococcus aureus.

February 9, 2026Open Access

Methylene Blue-Enhanced Photodynamic and Sonodynamic Therapy against Staphylococcus Aureus: From Laboratory Research to Clinical Evaluation

HKHana KolářováPalacký University Olomouc LVLucie VálkováInstitute of Molecular and Translational Medicine MKMarkéta KolaříkováInstitute of Molecular and Translational Medicine

Key Points

The aim is to evaluate the effectiveness of methylene blue-enhanced therapies against Staphylococcus aureus.
Assessment of methylene blue-mediated photodynamic therapy (PDT).
Evaluation of combined photodynamic and sonodynamic therapy (PDT+SDT).
Analysis of safety and tolerance in laboratory conditions.
Both therapies demonstrated safety and good tolerance.
Effective in targeting Staphylococcus aureus on skin.
Provided localized antimicrobial effects, bypassing antibiotic resistance.

Abstract

MB-mediated PDT and PDT+SDT are safe, well tolerated, and effective against S. aureus on skin. These approaches provide localized antimicrobial activity independent of antibiotic resistance and warrant further optimization for clinical application.

AI에게 질문

Bookmark

View Full Paper