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Meta-analysis reveals neutrophil-to-lymphocyte ratio's limited reliability in systemic lupus erythematosus, indicating need for combined assessments.
NLR is elevated in SLE, LN, and active disease, showing a weak positive correlation with disease activity. However, its clinical utility is influenced by ethnicity and treatment, indicating that it should not be used as an independent biomarker but may have a role as part of a combined assessment.
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Du et al. (2026) studied this question.
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