Research shows that a high fat diet affects metabolism and cognition differently in male and female Alzheimer’s mice, suggesting significant gender differences in disease progression.
AD females experienced greater metabolic, cognitive, and pathologic effects in response to a HFD compared to AD males and WT controls. These observations provide a better understanding of how metabolic disease may differentially affect the development of dementia in men and women.
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Sabourin et al. (2026) studied this question.
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