Assessment of New Flavouring Substance 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)imidazolidine-2,4-dione

“The FSA/FSS have undertaken an assessment of application RP 1382 for the authorisation of a new flavouring substance: 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)imidazolidine-2,4-dione flavour modifier of the bitter taste in various food categories. An alternative name is 2,4-Imidazolidinedione, 3-[1-[(3,5-dimethyl-4-isoxazolyl)methyl]-1H-pyrazol-4-yl]-1-[(3-hydroxy phenyl) methyl (synonymous to S6821) by Firmenich Belgium SA and Firmenich (UK). A food additive application has been received by Great Britain (GB) where the European Food Safety Authority (EFSA), prior to the end of the transition period, evaluated an application for the product. FSA/FSS has reviewed the EFSA opinion EFSA Journal 2016;14(7):4334) for this flavouring substance and confirmed that it is adequate and relevant for GB risk analysis. Therefore, the EFSA opinion was used to form the basis of the GB opinion. The FSA/FSS risk assessors concluded that the EFSA opinion is adequate and relevant for the risk analysis and therefore accepts the EFSA conclusion that 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)imidazolidine-2,4-dione, as described in this application, is not expected to be of concern at the intended levels of use.”