Radiographic Diagnosis of Florid Early Congenital Syphilis: The Enduring Relevance of the Skeletal Survey in the Era of Resurgent Syphilis

This record contains an archived neonatal clinical case report of early congenital syphilis originally prepared in 2017 and shared for educational and open-science purposes. The case describes a late-preterm, growth-restricted neonate born to an unbooked mother who presented with multisystem involvement, including hepatosplenomegaly, syphilitic rhinitis, hematological abnormalities, and classic skeletal manifestations. Radiographic evaluation demonstrated bilateral metaphyseal lucent bands, periostitis of the long bones, and the pathognomonic Wimberger sign, highlighting the enduring diagnostic value of the skeletal survey in congenital syphilis. Although advances in antenatal screening strategies and public health initiatives have occurred since the case was prepared, missed opportunities for prevention and delayed diagnosis continue to contribute to disease burden globally. Written informed consent was obtained at the time of original case preparation, all patient identifiers have been removed, and no new data or analyses are presented in this archived educational report.