Demonstrates high-grade transformations in SMARCA4-deficient pulmonary invasive mucinous adenocarcinoma, suggesting aggressive clinical behavior.
SMARCA4-deficient non-small cell lung cancer is characterized by highly aggressive clinical behavior, diverse tumor subtypes, and complex histological features. The application of the SMARCA4 immunohistochemical marker facilitates accurate identification. This study presents a rare case of SMARCA4-deficient pulmonary invasive mucinous adenocarcinoma with high-grade transformation.
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