Key result
Cutting and drug-coated balloons successfully treat very late LM chimney stent restenosis post-TAVR.
Why the study?
Despite the growing adoption of chimney stenting for coronary artery obstruction during TAVR, data on long-term outcomes and chimney stent in-stent restenosis are sparse.
Does cutting balloon and drug-coating balloon angioplasty successfully treat in-stent restenosis of a left main chimney stent post-TAVR?
Does cutting balloon and drug-coating balloon angioplasty successfully treat in-stent restenosis of a left main chimney stent post-TAVR?
Cutting balloon and drug-coated balloon angioplasty may be a viable treatment for in-stent restenosis of left main chimney stents following TAVR.
May be viable for very late left main chimney stent restenosis after TAVR; leaves open durability and generalizability.
Background Coronary artery obstruction (CAO) is a critical complication in transcatheter aortic valve replacement (TAVR). CAO arises from mechanical obstruction of coronary ostia by displaced native or bioprosthetic valve leaflets. Despite the growing adoption of chimney stenting, data on long-term outcomes are sparse. We introduced a patient who had undergone a very late in-stent restenosis (ISR) over the left main (LM) chimney stent and its successful management using a cutting balloon (CB) and drug coating balloon (DCB). Case Summary A patient experienced an angina symptoms 2 years after receiving TAVR with LM chimney stent placement. Coronary angiography revealed ISR of LM chimney stent in neosinus proportion. The patient was successfully treated by cutting balloon and drug coating balloon angioplasty. Discussion The chimney stent technique, initially developed as a bailout technique, is increasingly used prophylactically in anatomically high-risk cases. Lacking large-scale studies on chimney stent ISR limits our understanding. Besides CABG or repeat stenting, cutting balloon plus drug-coating balloon may offer a potential opinion to achieve long-term benefits in such cases. With rapid increasing of TAVR patient, further studies may be needed to guide the possible complication with chimney stent in CAO cases.
No takes yet. Share an insight, caveat, or question.
Hsieh et al. (2026) studied this question. Cutting balloon and drug-coating balloon angioplasty successfully treated very late in-stent restenosis of left main chimney stent post-TAVR in this case report.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: