The study shows a correlation between appendiceal inflammation and relapse risk in ulcerative colitis, suggesting clinical relevance.
Active appendiceal inflammation is prevalent in quiescent UC and showed a trend toward association with relapse risk. Although the benefit of appendicectomy in this group cannot be confirmed on these data alone, the finding might be clinically relevant as relapse rates are significantly reduced in the appendicectomy group.
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Visser et al. (2026) studied this question.
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