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February 9, 2026International Journal of Research and ReviewOpen Access

The Effect of Combined Platelet-Rich Plasma and Bone Graft for Bone Regeneration: A Systematic Review

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Authors

LKLeonardus William KuswaraPAPutu Pageh AstawaCDCokorda Gde Oka Dharmayuda

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Overview

Systematic review evaluates combined effect of platelet-rich plasma and bone graft on bone healing outcomes, suggesting significant improvements.

Key Points

  • This systematic review aims to assess the impact of combining platelet-rich plasma with bone grafts on bone healing outcomes compared to standard treatments.
  • Conducted a systematic review following PRISMA guidelines.
  • Explored articles from databases like PubMed and ScienceDirect over the last ten years.
  • Extracted data on study design, sample size, and outcomes from selected studies.
  • Identified seven studies with a total of 455 samples.
  • Functional scores were consistently higher in PRP groups, particularly the Harris Hip Score.
  • VAS scores were significantly lower in PRP groups at final follow-ups.
  • Healing and union rates were higher in PRP groups compared to controls.
  • PRP groups had shorter healing durations and lower complication rates than control groups.

Cite This Study

Kuswara et al. (2025) studied this question.

synapsesocial.com/papers/69897a14f0ec2af6756e8592https://doi.org/10.52403//ijrr.20250701
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