Prognostic ability of salivary S100B in predicting unfavorable outcomes in patients with moderate and severe traumatic brain injury

Lillian Caroline Fernandes; Dyenily Alessi Sloboda; Lilia de Souza Nogueira; Wellingson Silva Paiva; Leda Leme Talib; Cícero Augusto Costa Pereira; Augusto Magno Tranquezi Cordeiro; R.M.C. Sousa

doi:10.1080/02699052.2026.2625373

February 7, 2026Brain Injury

Prognostic ability of salivary S100B in predicting unfavorable outcomes in patients with moderate and severe traumatic brain injury

View Full Paper

Ask AI

Bookmark

Share

Key Points

This research aims to evaluate the prognostic ability of salivary S100B for predicting outcomes in traumatic brain injury patients.
Observed salivary S100B levels at 6 hours post-injury.
Compared salivary S100B levels with plasma and earlier saliva samples.
Analyzed the prognostic performance of salivary S100B.
Salivary S100B showed superior prognostic performance compared to plasma samples.
Earlier saliva samples had lower predictive ability than salivary S100B at 6 hours.
Salivary S100B is suggested as a reliable noninvasive biomarker for TBI prognosis.

Implication

Observational study evaluates salivary S100B as a noninvasive biomarker for predicting TBI outcomes, suggesting its clinical use.

Abstract

Salivary S100B at 6 hours post-TBI showed superior prognostic performance compared to plasma and earlier saliva samples, highlighting its potential as a noninvasive biomarker for TBI prognosis.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Fernandes et al. (2026) studied this question.

synapsesocial.com/papers/69897a25f0ec2af6756e8714 https://doi.org/10.1080/02699052.2026.2625373

View Full Paper

Ask AI

Bookmark

Share

Prognostic ability of salivary S100B in predicting unfavorable outcomes in patients with moderate and severe traumatic brain injury

Key Points

Implication

Abstract

Discussion

Cite This Study

Prognostic ability of salivary S100B in predicting unfavorable outcomes in patients with moderate and severe traumatic brain injury

Key Points

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading