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February 9, 2026Rapid Communications in Mass Spectrometry

Characterization of the Constituents of the Stem of Bauhinia championii (Benth.) Benth and Their Metabolites in Rat Plasma by UPLC‐LTQ/Orbitrap HRMS

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Authors

SDShiren DengHYHao YangXCXiaoxia Chen

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Overview

This analysis identifies constituents and metabolites in rat plasma from Bauhinia championii, suggesting its therapeutic potential.

Key Points

  • The study aims to identify and characterize the components and metabolites of Bauhinia championii in rat plasma for therapeutic applications.
  • Used ultraperformance liquid chromatography coupled with high resolution mass spectrometry (UPLC-LTQ/Orbitrap HRMS) to analyze extracts.
  • Identified constituents through MS2 profiles and comparative analysis with authentic standards and online libraries.
  • Analyzed data using Xcalibur to delineate constituent composition.
  • Identified 46 components in LXT extract, including 28 flavonoids and various other compounds.
  • First-time detection of 27 components in LXT extract.
  • 54 compounds were detected in rat plasma, consisting of 11 prototypes and 43 metabolites, suggesting pharmacodynamic relevance.

Cite This Study

Deng et al. (2026) studied this question.

synapsesocial.com/papers/69897a25f0ec2af6756e87e8https://doi.org/10.1002/rcm.70045
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