What question did this study set out to answer?

This research aims to assess how local anesthetic wound infiltration affects pain management during cesarean deliveries when combined with intrathecal opioids.

February 9, 2026PregnancyOpen Access

Wound infiltration with local anesthetics during cesarean delivery with intrathecal opioids: A systematic review and meta‐analysis of randomized control trials

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Authors

VFValentina FrusoneDrexel University KKKavisha KhanujaThomas Jefferson University JSJacqueline SinnottThomas Jefferson University Hospital

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Implication

This systematic review evaluates local anesthetic infiltration effects on pain in cesarean delivery patients receiving intrathecal opioids, suggesting significant benefits.

Key Points

This research aims to assess how local anesthetic wound infiltration affects pain management during cesarean deliveries when combined with intrathecal opioids.
Conducted a systematic review of randomized controlled trials (RCTs)
Evaluated anesthetic infiltration versus no infiltration during cesarean deliveries
Analyzed pain scores and opioid consumption at multiple time points post-surgery
Infiltration with local anesthetics significantly reduced pain scores with movement at 48 hours (MD, −9.07)
Decreased morphine consumption at 48 hours in the infiltration group (MD, −3.09)
Pain scores at rest were decreased but not statistically significant at 24, 48, and 72 hours

Cite This Study

Frusone et al. (2026) studied this question.

synapsesocial.com/papers/69897a86f0ec2af6756e8a78 https://doi.org/10.1002/pmf2.70240

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Implication

This systematic review evaluates local anesthetic infiltration effects on pain in cesarean delivery patients receiving intrathecal opioids, suggesting significant benefits.

Wound infiltration with local anesthetics during cesarean delivery with intrathecal opioids: A systematic review and meta‐analysis of randomized control trials

Discussion

Member takes

Implication

Key Points

Cite This Study

Wound infiltration with local anesthetics during cesarean delivery with intrathecal opioids: A systematic review and meta‐analysis of randomized control trials

Discussion

Member takes

Implication

Key Points

Cite This Study

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