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February 9, 2026Journal of Materials Chemistry B0 citations

Photothermal-Enhanced Oxygen-Releasing and Antibacterial Hydrogel Accelerating Diabetic Wound Healing via Energy Metabolism Regulation

MLMaojiao LiSichuan UniversityHZHuiyu ZhengSichuan UniversityYCYan ChenSichuan University

Key Points

  • The study aims to evaluate a hydrogel that enhances oxygen release and has antibacterial properties to facilitate wound healing in diabetic patients.
  • Developed a photothermal-enhanced hydrogel
  • Evaluated oxygen-releasing capabilities
  • Tested antibacterial effects
  • Assessed wound healing outcomes in diabetic models
  • Significant improvement in wound healing rates observed
  • Enhanced oxygen levels contributed to tissue repair
  • Reduced bacterial infection was noted
  • Energy metabolism regulation showed positive effects on healing

Abstract

Non-healing diabetic wounds represent a significant clinical challenge for diabetic patients, with hypoxia-driven microenvironmental remodeling and persistent infection being the primary barriers to effective tissue repair. To address these issues,...

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Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/69897a86f0ec2af6756e8b3ahttps://doi.org/10.1039/d6tb00018e
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Calcium Peroxide‐Based Hydrogel Patch with Sustainable Oxygenation for Diabetic Wound Healing2024 · 51 citations
  2. 2Kill Two Birds with One Stone: Dual‐Metal MOF‐Nanozyme‐Decorated Hydrogels with ROS‐Scavenging, Oxygen‐Generating, and Antibacterial Abilities for Accelerating Infected Diabetic Wound Healing2024 · 123 citations
  3. 3Oxygen‐Vacancy‐Engineered Self‐Regenerative Nanozymes in Dual‐Signal‐Responsive Dynamic Hydrogels: A Closed‐Loop Therapeutic Strategy for Diabetic Wound Microenvironment Remodeling2025
  4. 4Comprehensive Review of Hydrogel-Mediated Strategies for Diabetic Wound Healing2026 · 3 citations
  5. 5Hostile microenvironment-driven oxygenator hydrogel with spatiotemporally feedback regulated hif-1α for accelerating diabetic wound healing2026