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Frequency of tuberculosis variants suggests historical impacts on Native American populations, indicating further research needs.
The variants considered are associated with contemporary TB, and it is uncertain whether they were associated with TB in the past. Suggestions for further research: Our findings underscore the need for future studies on the origins and spread of tuberculosis and the selective pressures the disease may have exerted on human populations in the Americas before and after European contact.
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Cardouzo et al. (2026) studied this question.
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