Development and validation of a computed tomography myocardial perfusion imaging radiomic model for major adverse cardiovascular events prediction: a multicenter study.

Key Points

• To develop and validate a radiomic model using computed tomography myocardial perfusion imaging for predicting major adverse cardiovascular events.
• Utilized multiparametric CT-MPI maps for feature extraction.
• Combined radiomic features from macrovascular and microvascular assessments.
• Compared performance of the radiomic model to conventional predictive models.
• Radiomic model showed significantly improved prognostic performance compared to conventional models.
• Maintained high interpretability for clinical application.
• Effectively captured both macrovascular and microvascular perfusion features.