Design, synthesis and antitumor activity evaluation of 1,4-naphthoquinone-benzene sulfonamide hybrids

Key Points

• This research aims to evaluate the antitumor activity of 1,4-naphthoquinone-benzene sulfonamide hybrids, specifically compound 4m.
• Design and synthesis of 1,4-naphthoquinone-benzene sulfonamide hybrids
• Evaluation of antitumor activity against bladder cancer
• Compound 4m demonstrated potential as an anti-bladder cancer agent.