Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
February 11, 2026Eye OpenOpen Access

Two-to-three-year effectiveness and safety of nurse-led accelerated corneal crosslinking for progressive keratoconus: The Birmingham and Midland Eye Centre Study

View Full Paper
Ask AI
Bookmark
Share

Authors

MKMurad KhanBirmingham and Midland Eye CentreRSRashvinder SahotaBirmingham and Midland Eye CentreJHJoan HansonBirmingham and Midland Eye Centre

Discussion

Loading...

Member takes

Implication

Evaluates the effectiveness and safety of nurse-led accelerated corneal crosslinking for keratoconus, suggesting its feasibility for eye care services.

Key Points

  • To assess the effectiveness and safety of nurse-led accelerated corneal crosslinking for progressive keratoconus over two to three years.
  • Included patients with progressive keratoconus undergoing nurse-led CXL from February 2019 to December 2021.
  • Used a standardized epithelium-off CXL protocol with 10 mW/cm² UV-A irradiation for 9 minutes.
  • Analyzed data including demographics, visual acuity, corneal measurements, and adverse events.
  • Significant improvement in corrected-distance-visual-acuity from baseline to 24 months (p < 0.001).
  • Significant reduction in Kmax measurements from baseline to 24 months (p < 0.001).
  • Stable CDVA and significant Kmax improvement at 36 months post-CXL (p < 0.001).
  • Only 3 cases (3.1%) of transient corneal haze observed with no severe adverse events.

Cite This Study

Khan et al. (2026) studied this question.

synapsesocial.com/papers/698c1c8e267fb587c655f130https://doi.org/10.1038/s44440-026-00013-z
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Changing trends in keratoplasty in the West of Scotland: a 10-year review2011 · 85 citations
  2. 2Comparison of standard versus accelerated corneal collagen cross-linking for keratoconus: 5-year outcomes from the Save Sight Keratoconus Registry2023 · 35 citations
  3. 3Standard and accelerated corneal cross-linking long-term results: A randomized clinical trial2019 · 36 citations
  4. 4Dramatic Reduction in Corneal Transplants for Keratoconus 15 Years After the Introduction of Corneal Collagen Crosslinking2023 · 22 citations