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February 11, 2026Annals of Medicine and SurgeryOpen Access

Survival analysis and prognostic factors for gastrointestinal and extragastrointestinal stromal tumors: a SEER-based study

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Authors

WAWael AlkattanMAMarwan AlaswadTATarek Ziad Arabi

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Overview

This retrospective analysis evaluates survival outcomes in GIST and EGIST patients, suggesting significant prognostic factors.

Key Points

  • This study aims to analyze survival outcomes and identify prognostic factors associated with GIST and EGIST patients.
  • Retrospective review of GIST cases from the SEER database.
  • Included 18,819 patients with 918 classified as EGIST.
  • Analyzed overall survival and cancer-specific survival across different demographic groups.
  • Median overall survival and cancer-specific survival were not reached.
  • GIST patients had significantly longer cancer-specific survival compared to EGIST patients.
  • Factors associated with shorter cancer-specific survival included EGIST, male gender, regional disease, and age.
  • Surgery was found to be a protective factor for survival.

Cite This Study

Alkattan et al. (2025) studied this question.

synapsesocial.com/papers/698c1cd3267fb587c655f8ebhttps://doi.org/10.1097/ms9.0000000000004140
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prognostic Factors for Survival in Surgically Treated Patients with Gastrointestinal Stromal Tumors: A Single-Center 15-Year Retrospective Analysis2026
  2. 2Clinical Experience with Gastrointestinal Stromal Tumors: A Retrospective Analysis2025 · 1 citations
  3. 3Retrospective analysis of clinicopathological characteristics and survival outcome of gastrointestinal stromal tumors: Real-world experience2026
  4. 4Long-term oncologic outcomes following endoscopic versus surgical resection for GISTs: a propensity score matching analysis in the SEER database2026
  5. 5Endoscopic therapy versus surgical resection for rectal gastrointestinal stromal tumors: a population-based comparative analysis of long-term survival outcomes2025