What question did this study set out to answer?

February 11, 2026PLoS ONEOpen Access

Protocol of a multi-centre randomized controlled trial to compare pericapsular nerve group block, fascia-iliaca compartment block and femoral nerve block for pain management in patients with a hip fracture in the emergency department (CPFF-ED)

View Full Paper

Ask AI

Bookmark

Authors

Multicentre RCT compares pain relief effectiveness of nerve blocks in elderly patients with hip fractures, suggesting safer alternatives to opioids.

To evaluate the efficacy and safety of pericapsular nerve block, fascia iliaca compartment block, and femoral nerve block for managing pain in hip fracture patients.
Conducted a multicentre randomized controlled trial in the emergency department of five hospitals.
Involved 254 adult patients with neck of femur or pertrochanteric femur fractures.
Patients randomized to receive one of the three nerve blocks after informed consent.
Followed for 12 hours post-block placement, measuring outcomes with the QoR-15 questionnaire.
Primary outcome measures include patient wellbeing at 6-8 hours post-block administration.
Secondary measures assess pre-operative pain scores and analgesic use in the first 12 hours.
Expectation to determine the most effective nerve block for improving pre-operative wellbeing.

Dolstra et al. (2026) studied this question.

View Full Paper

Ask AI

Bookmark

Multicentre RCT compares pain relief effectiveness of nerve blocks in elderly patients with hip fractures, suggesting safer alternatives to opioids.