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February 12, 2026The American Journal of Cardiology1 citationsOpen Access

Radial versus femoral secondary access in patients undergoing TAVI - Rationale and Design of the RADIAL-TAVI trial

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AEAlexander von EhrUZUwe ZeymerSSSteffen Schneider

Key Result

The RADIAL-TAVI trial aims to determine if radial secondary access is superior to femoral in transfemoral TAVI to reduce complications and improve outcomes.

Key Points

  • The trial aims to assess whether radial access is superior to femoral access in transfemoral TAVI procedures.
  • Randomized trial design
  • Patient population undergoing transfemoral TAVI
  • Comparison of secondary access strategies: radial versus femoral access
  • Evaluation of complication rates and patient outcomes
  • Radial access may reduce complication rates
  • Potential for improved patient safety
  • Implications for redefining standard practice in TAVI procedures

Structured PICO

Does radial secondary access reduce complication rates and improve safety compared to femoral secondary access in patients undergoing transfemoral TAVI?

P
Population
Patients undergoing transfemoral transcatheter aortic valve implantation (TAVI)
I
Intervention
Radial secondary access
C
Comparator
Femoral secondary access

The RADIAL-TAVI trial is designed to provide the first randomized evidence comparing radial versus femoral secondary access in transfemoral TAVI.

Abstract

The RADIAL-TAVI trial will provide the first randomized evidence on the optimal secondary access strategy in transfemoral TAVI. If radial access proves superior, it has the potential to redefine standard practice, reduce complication rates, and improve patient safety and outcomes.

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Cite This Study

Ehr et al. (2026) studied this question. The RADIAL-TAVI trial aims to determine if radial secondary access is superior to femoral in transfemoral TAVI to reduce complications and improve outcomes.

synapsesocial.com/papers/698d6d445be6419ac0d5227dhttps://doi.org/10.1016/j.amjcard.2026.01.016
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