Demonstrates the association between mucosal impedance and mucosal integrity in patients with refractory reflux-like symptoms, suggesting its potential as a diagnostic tool.
Mid-esophageal mucosal impedance reflects impairment of mucosal integrity and may contribute to the physiological phenotyping of patients with rRLS. Location-specific impedance assessment could serve as a complementary tool to conventional reflux testing, aiding in mechanism-based classification. However, it should not be used in isolation to guide therapeutic decisions.
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Li et al. (2026) studied this question.
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