What question did this study set out to answer?

This research aims to assess the antiparasitic properties of Senna alata leaf extract against Hymenolepis diminuta in rodents.

February 12, 2026Open Access

Preclinical evaluation of Senna alata leaf extract against Hymenolepis diminuta: a promising natural anthelmintic solution

SRSaptarshi RoyVisva-Bharati University LLLarisha M. Lyndem

Key Points

This research aims to assess the antiparasitic properties of Senna alata leaf extract against Hymenolepis diminuta in rodents.
Utilized a rodent model infected with Hymenolepis diminuta.
Administered alcoholic leaf extract of Senna alata at a dosage of 1000 mg/kg.
Monitored hematological and organ function parameters throughout the study.
Senna alata leaf extract demonstrated strong antiparasitic efficacy against Hymenolepis diminuta.
Administered extract significantly improved host hematological parameters.
Extract was found to be non-toxic, supporting its use as a natural anthelmintic.

Abstract

This study demonstrates the potent antiparasitic effects of S. alata against H. diminuta in a rodent model. The alcoholic leaf extract of S. alata, particularly at 1000 mg/kg, exhibits strong antiparasitic efficacy against H. diminuta, alongside notable improvements in host hematological and organ function parameters. Its non-toxic nature reinforces its potential as a safe, natural anthelmintic, warranting further exploration for therapeutic applications.

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