Pilot RCT shows urine tenofovir feedback improves PrEP adherence in young MSM, suggesting effective intervention.
A remote, motivational interviewing–informed intervention using self-administered point-of-care urine tenofovir testing improved long-term pre-exposure prophylaxis (PrEP) adherence among young U.S. men-who-have-sex-with-men in a pilot randomized trial. Participants increased hair tenofovir levels by one to two tablets weekly, with high feasibility and acceptability, supporting further implementation.
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Spinelli et al. (2026) studied this question.
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